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Longman Dictionary of Contemporary English
malignancy
noun
EXAMPLES FROM CORPUS
▪ However, all malignancies must be suspected of participating in hypercalcemia.
▪ Occasionally, primary hyperparathyroidism has been known to occur concurrently with a malignancy, but this is very rare.
▪ Pancreatic carcinoma is now overtaking gastric cancer as the fourth leading cause of death from malignancy in the United Kingdom.
▪ Soothing an internal malignancy may do more harm than good.
▪ The work, if confirmed, could eventually lead to clinical application in the treatment of aplastic anaemia and malignancy.
▪ This might open up new concepts for influencing local tumour growth and metastasis of colonic malignancies.
▪ Traditional psychodynamic individual work is perhaps the most intense way to excise emotional malignancies that are getting in your way at work.
The Collaborative International Dictionary
Malignancy

Malignance \Ma*lig"nance\, Malignancy \Ma*lig"nan*cy\, n. [See Malignant.]

  1. The state or quality of being malignant; extreme malevolence; bitter enmity; malice; disposition toward evil; intense ill will; as, malignancy of heart.

  2. Unfavorableness; evil nature.

    The malignancy of my fate might perhaps distemner yours.
    --Shak.

  3. (Med.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.

  4. Hence: (Med.) A cancerous tumor that is spreading beyond the point of origin.

    Syn: malignant tumor, malignant neoplasm, metastatic tumor.

  5. The state of being a malignant.

Douglas Harper's Etymology Dictionary
malignancy

c.1600, "malignant nature," from malignant + -cy. Of growths, tumors, from 1680s.

Wiktionary
malignancy

n. 1 The state of being malignant or diseased. 2 A malignant cancer; specifically, any neoplasm that is invasive or otherwise not benign. 3 That which is malign; evil, depravity, malevolence.

WordNet
malignancy
  1. n. (medicine) a malignant state; progressive and resistant to treatment and tending to cause death [syn: malignance]

  2. quality of being disposed to evil; intense ill will [syn: malignity, malignance] [ant: benignity, benignity]

Wikipedia
Malignancy

Malignancy is the tendency of a medical condition to become progressively worse.

Malignancy is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties.

Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their entire genomes. Cancers usually show tumour heterogeneity, containing multiple subclones. They also frequently have reduced expression of DNA repair enzymes due to epigenetic methylation of DNA repair genes or altered microRNAs that control DNA repair gene expression.

Uses of "malignant" in oncology:

  • Malignancy, malignant neoplasm and malignant tumor are synonymous with cancer
  • Malignant ascites
  • Malignant transformation

Non-oncologic disorders referred to as "malignant":

  • Malignant hypertension
  • Malignant hyperthermia
  • '' Malignant otitis externa
  • Malignant tertian malaria (malaria caused specifically by Plasmodium falciparum)
  • Neuroleptic malignant syndrome
Malignancy (band)

Malignancy is a technical death metal band from Yonkers, New York formed in February 1992.

Malignancy (disambiguation)

Malignancy is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death.

Malignancy may also refer to:

  • Malignancy (band), a technical death metal band
  • Malignant (Law & Order: Criminal Intent), an episode of Criminal Intent
  • Malignant (film), a 2013 American horror film

Usage examples of "malignancy".

This thing, which seemed instinct with a fearsome and unnatural malignancy, was of a somewhat bloated corpulence, and squatted evilly on a rectangular block or pedestal covered with undecipherable characters.

She sensed no malignancy, simply the presence of something vastly larger than herself.

Flinx felt it as a suppurating malignancy, an utter absence of mitigating humanity.

The pain suppressants in his system were doing a good job of keeping him from noticing the progress of the bloodborne malignancy that was attacking his heart muscle, consuming him layer by layer from the inside.

Then, when even the blotched and sickly cacti became more sparse and stunted, and rills of ashen sand crept in among them, I began to suspect how great was the hatred my heresy had aroused in the priests of Ong and to guess the ultimate malignancy of their vengeance.

He had seen many things and was both gratified and horrified: gratified that he had uncovered several key elements of the mystery that would help Calis best decide what to do next, and horrified because in his long life he had never met a gathering of evil men so concentrated in both numbers and malignancy.

While these possibilities ran past his inner scrutineer a remote corner of his mind called out shrilly against the injustice of missing stays - unknown in such conditions, monstrous, a malignancy designed to make him late on his station, to allow Harte to call him unofficerlike, no seaman, a dawdling Sybarite, a slow-arse.

At one point she had considered disarticulating at the hip in the belief that this might give a better chance of getting ahead of the spreading malignancy from the knee.

Patches of shining white cheekbone protruded through the flesh of the face, knuckles pierced the skin of the hands, and even where the skin remained intact it looked like there was some malignancy crawling across it and discoloring it.

Patches of shining white cheekbone protruded through the flesh of the face, knuckles pierced the skin of the hands, and even where the skin remained intact it looked like there was some hideous malignancy crawling across it and discoloring it.

Randi Harlengen had gotten her tubes tied, they took cysts as big as golf-balls out of her ovaries, no malignancy, thank God, but twenty-seven ovarian cysts, could you die!

On average, humans suffer one fatal malignancy for each 100 million billion cell divisions.

Charlotte's marrow was producing little new blood, and indications were that malignancy was inhibiting blood-cell formation.

Maybe then, if the malignancy hadn't gotten into her brain and killed her, maybe then she would at last do the right thing with a tailpipe or a gas oven, or a shotgun.

With the interferons and other immunological amplifiers we have, we could stimulate her body to throw off the malignancy.